BIOENSIS Oncolytic Virus tools can be used for efficacy evaluation in 2D and 3D micro-tissues and include immune-cell killing, cell proliferation and phagocytosis assays,
Cell proliferation assays offers a systematic method to screen Oncolytic Viruses against a panel of cancer cell lines for the evaluation of efficacy and biomarker association. Our 2D/3D cultures are grown under physiologically relevant conditions that better predict in vivo activity, thus allowing for confident selection of promising drug candidates for further testing and reducing the risk of costly “false starts.”
Cell invasion/migration assays monitor the activity of test articles in their role in cancer initiation, tumor progression and metastasis as well as tissue remodeling. BIOENSIS' invasion assays are designed to quantify the efficacy of a compound’s capability to inhibit invasive metastatic and endothelial cell movement across a basement membrane.
Immune-cell killing assays test for the ability of therapeutic antibodies to stimulate T cells and NK cells to kill cancer target cells.
Phagocytosis assays tests for the killing of cancer cells via phagocytosis by monocyte-derived macrophages.
Please contact us to discuss your study and an up to date list of available cell lines info@bioensis.com
